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Module TRANSLATIONAL CLINICAL RESEARCH

Module code: BI433
Credits: 5
Semester: 1
Department: BIOLOGY
International: Yes
Coordinator: Dr Paul Dowling (BIOLOGY)
Overview Overview
 

This module focuses on examples of how fundamental laboratory-based research has led to improvements in the diagnosis of, or therapy for, diseases. Students will also gain understanding of technologies used for bioproduct generation and the in vitro diagnostics and blood product industry. The module examines the development of novel diagnostics and therapeutics and shows how these have been brought through clinical trials, obtained regulatory clearance, and introduced into routine clinical practice. Case studies focus on the development of an innovative Parvovirus diagnostic assay or high sensitivity detection systems. How murine animal models are used in medical research to identify new drug targets will be discussed. Candidate biologic therapies in clinical use for the treatment of inflammatory diseases and the development of ‘checkpoint inhibitors’ for cancer immunotherapy will be explored. The course also focuses on the different types of molecular targets that can be exploited in drug development with specific emphasis on how basic research around receptor signaling pathways has contributed to the discovery of new anti-inflammatory drugs. This module examines the link between fundamental research and clinical practice and demonstrates how the two activities are mutually beneficial in terms of patient care and therapy.

Open Learning Outcomes
 
Open Teaching & Learning methods
 
Open Assessment
 
Open Autumn Supplementals/Resits
 
Open Pre-Requisites
 
Open Timetable
 
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