On successful completion of the module, students should be able to:
- Describe the various reagents and methods used for recombinant DNA technology and explain how these are applied to research and diagnostics.
- Describe the processes of transcription, mRNA processing, and translation.
- Explain in detail how eukaryotic gene expression can be regulated transcriptionally and post-transcriptionally.
- Define the term epigenetics and relate this to gene expression.
- Describe chromatin and explain how chromatin status can influence gene expression.
- Distinguish between different classes of mobile genetic elements present in prokaryotic and eukaryotic genomes.
- Describe the various sequence elements that are present in eukaryotic genomes and discuss how they influence genome size and organisation.
- Describe with examples how mobile genetic elements can influence gene expression and organismal phenotype.