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This module will have a strong emphasis on proteins, the regulation of their activity and their participation to cellular processes. There will also be a particular focus on essential metabolic pathways, which will be described in detail, but also presented within a physiological context. An effort will be made to present simple experimental evidence for essential concepts. Tutorials will focus on developing problem-solving and analytical skills.
The following topics will be covered: - Introduction to biochemistry and a brief reminder of important notions related to proteins. - Enzyme kinetics, including enzyme inhibition and applications for drug design. - Basic concepts of metabolism and bioenergetics. - Detailed description of essential metabolic pathways such as glycolysis, citric acid cycle, oxidative phosphorylation and photosynthesis. - Methods in biochemistry, including protein purification, monitoring enzyme activity, pigment extraction and separation.
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